When there is respiratory infectious disease, it needs to be actively treated with effective antimicrobial drugs, which can use penicillin or cephalosporin antimicrobial drugs, and also can use quinolone drugs for comprehensive treatment. At present, the main use of the third generation of quinolones, commonly used drugs are ofloxacin, ciprofloxacin, levofloxacin, but also the fourth generation of quinolones, commonly used drugs are moxifloxacin, for the gram-negative and positive bacteria, as well as mycoplasma, chlamydia infectious diseases, have a very good antibacterial and anti-inflammatory effect. However, patients under the age of eighteen should not take these drugs orally, which will affect the development of bones, and sensitive antibacterial drugs can be selected according to the specific situation, and drug sensitivity tests can be done to choose.