The difference between Night Brightening Sand and Wuling Resin is the source, properties, efficacy, contraindications and precautions are different. For example, night brightening sand has the effect of clearing the liver and improving eyesight, dispersing blood stasis and eliminating accumulation of stagnant blood; five spirit has the effect of activating blood circulation, removing blood stasis and relieving pain. 1. Different sources and properties: nightshade is bat droppings, pungent in taste and cold in nature; wulingxin is the dried feces of flying squirrels and flying squirrels, bitter in taste, salty in taste, sweet in nature and warm in nature. Both drugs belong to the liver meridian. 2. Indications: Night Brightening Sand is mainly used for liver-heat and eye redness, white eye overflow, green blindness, corneal cataract, chancre, scrofula (mainly refers to cervical lymph node nodule tuberculosis), malaria, bruises, etc. Wuling Resin is used for thoracic and hypochondriac (chest and ribs), epigastric (stomach and abdomen) stabbing pains, menstrual cramps, menstrual closure, post-partum blood stasis and pains. 3. Contraindications and precautions are different: pregnant women should be cautious of nightshade; blood deficiency without blood stasis and pregnant women should be cautious of wulingzhi, ginseng is afraid of wulingzhi and should not be used together. Night-minding sand and Wu Ling Lipid should be used reasonably under the guidance of traditional Chinese medicine practitioners, and should not be confused as a kind of medicine, so as to avoid the adverse effects caused by wrong use of the medicine.