Lijunsha is the trade name, generic name of erythromycin ethylsuccinate, and roxithromycin belongs to the same class of macrolide antibiotics; there is no which effect is good, should be under the guidance of a physician, follow the doctor’s instructions to use the drug. 1. Erythromycin: ethyl succinate of erythromycin, more stable than erythromycin in gastric acid, can pass through the bacterial cell membrane, thus inhibiting bacterial protein synthesis; staphylococcus genus (except methicillin-resistant strains), Neisseria, chlamydia and mycoplasma, groups of streptococci and gram-positive bacilli, etc. have a role. Adverse reactions include nausea, vomiting, loss of appetite, abdominal distension, diarrhea, skin rash, liver damage, tinnitus, hearing impairment, etc.; hepatic insufficiency, pregnant women, lactating women, use with caution. 2. Roxithromycin is commonly used in the form of tablets, capsules, granules, etc. It is used for pharyngitis and tonsillitis caused by Streptococcus pyogenes, sinusitis caused by sensitive bacteria, upper respiratory tract infections, pneumonia caused by Mycoplasma pneumoniae or Chlamydia pneumoniae, and soft-tissue infections of skin caused by sensitive bacteria, etc. Adverse reactions include abdominal pain, diarrhea, and diarrhea. Adverse reactions include abdominal pain, diarrhea, nausea, vomiting, occasional rash, skin itching, dizziness, headache, abnormal liver function, peripheral blood cell decline. It is contraindicated for those who are allergic to this product, erythromycin or other macrolides, and is contraindicated in combination with ergotamine and dihydroergotamine. As the above drugs belong to the same class of macrolide antibiotics, antibacterial spectrum is also basically the same, should be based on the patient’s specific disease, sensitivity to drugs and adverse reactions, indications and other factors, comprehensive consideration, under the guidance of the physician to select the appropriate drugs for the patient to use, not blindly use their own medication.