Low total cholesterol may be related to malnutrition, hyperthyroidism, or severe liver disease. Different treatments can be given depending on the cause, such as dietary modification or medication and surgery. 1. Malnutrition: Low cholesterol intake due to picky eating or dieting leads to low total cholesterol, and malnutrition will occur in the long run. Patients need to adjust their dietary habits, eat a balanced diet, and supplement high-protein foods such as meat and eggs. 2. Hyperthyroidism: patients suffering from hyperthyroidism lead to excessive secretion of thyroid hormones, making the body in a long-term high consumption state, so that the protein decomposition consumes too much, thus leading to the performance of low total cholesterol. Drug therapy can be used, iodine can inhibit the hydrolysis of thyroglobulin to reduce the secretion of thyroid hormone to prevent cholesterol consumption, such as oral iodine. 3. Severe liver disease: If the patient suffers from hepatitis, cirrhosis, liver cancer and other diseases, the liver cell damage is serious, resulting in cholesterol synthesis disorder, leading to the occurrence of low total cholesterol. Follow the doctor’s advice to actively treat liver diseases, commonly used drugs for detoxification and protection of stem cell membranes, such as reduced glutathione tablets. In case of liver cancer and other malignant tumors, surgical treatment can also be adopted to remove the malignant lesions of liver tumors, so that the liver cells can gradually restore the normal function. It is recommended that patients with low total cholesterol should go to regular hospitals for further examination to clarify the cause of the disease, and take symptomatic treatment according to the doctor’s instructions, and do not take medication on your own in order to avoid delaying the condition.