Postural hypotension can be caused by autonomic nerve damage and is treated as follows: 1. Prevent aggravating factors: too rapid change of position, morning, large meals, prolonged leaning, warm environment, increased chest pressure (coughing, urination and defecation) and vasodilator drugs. 2. elastic stockings 3. reduce salt loss, take fludrocortisone 0.1mg /day 4. vasoconstrictor drugs increase vascular resistance, midodrine 10mg 2-3 times /day, phenylpropanolamine 25mg 3 times /day volume reduction: dihydroergotamine indirect drugs: ephedrine 5. prevent vasodilation Prostaglandin synthase inhibitors: indomethacin (anti-inflammatory pain) and flurbiprofen Dopamine receptor blockers. β-2 adrenergic receptor blockers: propranolol (Prostaglandin) 6. Prevent postprandial hypotension Prevent gastric filling: small meals Adenosine receptor blockers: caffeine Strong coffee or tea before rising or before meals Drinking water: rapid drinking, 120 – 480 ml of water 5 minutes before meals, 2 – 3 liters of water per day Activity, increased norepinephrine Peptide release inhibitors: growth inhibitor analogs; oxytocin Other drugs: ibuprofen 400 mg; phenylpropanolamine 25 mg; ephedrine nasal drops 1 to 2 times 7. increase cardiac output: cardiotonic and zamotrope 8. increase red blood cell count: erythropoietin 9. reduce nocturnal polyuria: desmopressin 10. reduce diastolic falls, bromiphosphine 11. prevent recumbent hypertension: reduce fludrocortisone, no vasoconstrictor drugs after 6 pm, use ACE inhibitors Sleep depillarization, use of ACE inhibitor enalapril (maximum amount after going to bed)