Nine-valent is generally recommended to be taken before the age of 45 is more appropriate. Nine-valent refers to the nine-valent human papillomavirus (HPV) vaccine, which is mainly used to prevent HPV infections. The nine subtypes of the virus that can be prevented are HPV subtypes 6, 11, 16, 18, 31, 33, 45, 52, and 58, and the age of this vaccine is 9-45 years old. The risk of exposure to HPV increases with age, especially with the onset of sexual activity, so it is recommended that age-eligible women receive the vaccine as early as possible. The HPV vaccine is a prophylactic vaccine that does not cure existing HPV infections and related diseases, does not prevent all HPV types of infections, and does not stop HPV infections from progressing to disease progression. Therefore, regular cervical cancer screening is still needed after HPV vaccination. Women who are pregnant or preparing for pregnancy should delay vaccination until the end of pregnancy, and breastfeeding women should exercise caution when receiving the vaccine. HPV vaccination is contraindicated in persons who have hypersensitivity to the active ingredient of the vaccine or to any of the excipient components, and persons who have symptoms of hypersensitivity after injection of the product should not be revaccinated with the product.