1, the use of a smaller effective dose, in order to obtain the efficacy and minimize adverse reactions, gradually increase the dose or combination of drugs, and strive to achieve blood pressure within 3 months; 2, in order to effectively prevent target organ damage, requiring 24 hours a day blood pressure stability within the target range, and actively recommend the use of a day to give a long-acting drugs and the efficacy can last 24 hours, if the use of medium-acting or short-acting drugs, the need for 2-3 times a day; 3, in order to increase the antihypertensive effect without increasing adverse reactions In order to increase the antihypertensive effect without increasing the adverse effects, the combination of two or more antihypertensive drugs with different mechanisms of action can be used. In the actual treatment process, the combination of antihypertensive drugs is often needed to achieve the target blood pressure in patients with grade 2 or higher hypertension or high risk; 4, individualized treatment: according to the specific circumstances of the patient, the choice of antihypertensive drugs more suitable for patients; research has proved that only 30-60% of patients can be controlled with a single drug, while the combination of drugs can increase the efficiency to 75%-90%. Because 2 or more types of antihypertensive drugs, which have different mechanisms of action, can achieve synergistic antihypertensive efficacy, while making adverse reactions offset each other, increasing patient compliance, but should avoid the combination of two drugs of the same type.