ICC is considered in the liver meaning that the patient may have intrahepatic cholangiocarcinoma. Intrahepatic cholangiocarcinoma, abbreviated as ICC, mostly originates from bile duct epithelial cells in the liver and most of them are adenocarcinomas, which account for about 10% of malignant primary hepatocellular tumors. If the cancer cells originate from both intrahepatic biliary epithelial cells and hepatocytes, it is called mixed type of cancer, which is less common. Epidemiologic evidence suggests that ICC is associated with HCV infection, cirrhosis, and others. The most common symptoms of intrahepatic cholangiocarcinoma are right upper abdominal pain and weight loss, and jaundice is present in about 25% of patients.ICC appears as a focal hepatic mass on CT and MRI, and the bile ducts around the mass may be dilated, and enhancement scans typically show enhancement around the periphery or center of the mass. The effective treatment for intrahepatic cholangiocarcinoma is hepatic resection. If patients are diagnosed with intrahepatic cholangiocarcinoma, they should actively cooperate with doctor’s treatment, which should be carried out according to doctor’s prescription.