Dakine generic name is miconazole nitrate cream, vesiculobullous foot odor that is impregnated vesiculobullous tinea pedis. The disease with miconazole nitrate cream more serious, indicating that the use of drugs is not targeted, the amount of drugs is not enough or adverse drug reactions, you can adjust the use of drugs, strengthen the amount of drugs or stop the drug. 1. medication is not targeted: impregnated vesicular tinea pedis can indeed use miconazole nitrate cream to kill the fungus, but in the beginning, the later more serious, or accompanied by other skin problems, the use of miconazole nitrate cream is inappropriate, can not stop the development of the disease. It is recommended that you can figure out the situation of macerated vesicular tinea pedis, and then targeted medication. 2. insufficient dosage: patients with macerated tinea pedis use miconazole nitrate cream in insufficient quantities, and the symptoms are more serious after using the drug. It is recommended to strengthen the amount of miconazole nitrate cream, and increase the number of times a day to use miconazole nitrate cream. 3. Adverse drug reactions: although miconazole nitrate cream is one of the drugs for the treatment of macerated tinea pedis, but the use of miconazole nitrate cream may appear blisters, congestion, allergies, itching, burning sensation and other adverse reactions, which make the patient feel that the condition has become serious. It is recommended that you can stop using miconazole nitrate cream at this point. It is contraindicated in case of allergy to miconazole nitrate cream. The use of miconazole nitrate cream in patients with macerated erosive tinea pedis needs to be directed by a doctor.