Total bilirubin 145 is high in one-month-old infants, which is usually not considered high, and most of the considerations may be caused by breast milk jaundice, which is physiologic. However, if the bilirubin continues to increase and other symptoms appear, it is considered to be hepatocellular jaundice, hemolytic jaundice, etc. It is recommended to use medication such as gammaglobulin and other surgical treatments to deal with it.
1. Breast milk jaundice: It may be related to the increase in the enterohepatic cycle of bilirubin metabolism in newborns, resulting in some one-month-old infants briefly showing a total bilirubin of 145 μmol/L. Generally, no special treatment is needed.
2. Hepatocellular jaundice: refers to jaundice in one-month-old infants caused by damage to liver cells, which may also be caused by biliary atresia in infants. Total bilirubin of 145 μmol/L may be present after the onset of jaundice, accompanied by symptoms such as ascites and liver failure. Usually, glutathione can be given to protect liver function, and surgery can be performed if necessary.
3. Hemolytic jaundice: due to the massive destruction of red blood cells, the content of unconjugated bilirubin in the blood exceeds the normal level, and the total bilirubin of 145 μmol/L can be seen, accompanied by the yellowing of the skin and mucous membranes and other clinical manifestations. Blue light irradiation treatment and medication, such as gammaglobulin, can be chosen. For some infants with more serious conditions, blood exchange therapy is required under strict medical supervision.
Total bilirubin 145 in one-month-old infants may also have other causes, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy. All of the above medications should be used under the guidance of a doctor, avoid self-medication.