The presence of leukoplakia on the glans should rule out specific infectious agents, such as fungal infections, which typically appear as a white film or localized leukoplakia-like changes on the glans. In this case, local secretion smear examination can find the specific pathogen. At the same time targeted antimicrobial treatment, you can apply antifungal ointment such as Dakinin; or take antifungal drugs such as ketoconazole, voriconazole, itraconazole and so on. If a woman has a fungal infection, she should be treated as a couple, and can be given vaginal suppositories such as nifurtimox mycotoxin vaginal suppositories; or oral medications as well as gynecological lotions can be used. In addition to infectious factors, some cases are seen in the immunogenic factors of the body, such as skin and mucous membrane leukoplakia. These leukoplakia-like lesions are dermatologic allergic diseases and should be treated with regular dermatologic therapy to get rid of them.