Closed mouth is actually acne, is due to the sebaceous gland secretion, follicle opening keratinization abnormality caused by squeezing acne need to be from the disinfection, daily care, dietary habits, and so on, if necessary, the use of medication. 1. Daily care Disinfection: After squeezing the acne, you can use a cotton ball to dip some disinfectant, such as povidone-iodine, etc. Povidone-iodine is less irritating to the skin, and disinfect the squeezed skin. Do not touch the squeezed area with your hands to avoid localized infection in the broken area. Do not use ointment cosmetics when the peak of oil production is not well controlled. Maintain a relaxed mood, good sleep, avoid staying up late and so on. Avoid spicy and stimulating food, keep a light diet. Eat more fresh vegetables and fruits. Control the intake of fat and sugar, avoid smoking and drinking. 2. Medication: Vitamin A cream, adapalene and other medications can be used as prescribed by the doctor. It is recommended that acne symptoms continue to be unrelieved or aggravated timely medical treatment, under the guidance of the doctor for targeted treatment or treatment.