The burning pain in the urinary orifice is as follows: 1. Consider a urinary tract infection, it is recommended that a routine urine examination be taken to confirm the diagnosis, if there is indeed an infection, oral antibiotic medication is required for treatment, drugs can choose quinolone antibiotics, such as ciprofloxacin 1 tablet, 3 times a day; or levofloxacin capsule 1 capsule, 3 times a day, continuous oral 5-7 days; 2. Mycoplasma, chlamydia, to rule out mycoplasma, chlamydia infection caused by. If the urethra has white or yellow thin-like discharge, accompanied by burning in the urethra, the possibility of mycoplasma, chlamydia infection is greater, you need to retain the secretion to do mycoplasma, chlamydia culture, if the culture of mycoplasma, chlamydia, we recommend the use of roxithromycin capsules 0.15g, twice a day; or intravenous azithromycin 0.5g drip, once a day, continuous sedation for 1 week; 3, local cleaning. Keep the urethral opening dry and clean. If there is secretion, it needs to be removed in time, you can use iodophor swabs to disinfect the external urethral opening.