There is pain in the stomach in the middle of the night, mainly due to these reasons: 1, irregularities in life and rest. The company’s main business is to provide a wide range of products and services to its customers, including: 1) irregularities in lifestyle, 2) late nights and improper diet, which can cause gastrointestinal discomfort and even stomach pain. 2) gastrointestinal diseases. The appearance of duodenal ulcer, gastritis and other diseases will affect the health of the stomach, resulting in damage to the mucosa of the stomach, resulting in the onset of midnight, stomach pain. 3, excessive stomach acid. Stomach acid is easily overproduced at night, and too much stomach acid at night will cause stimulation of the gastric mucosa, resulting in the appearance of stomach pain in the middle of the night. 4. Decreased defense mechanism of the duodenal mucosa. As the defense mechanism of the duodenum decreases, it will lead to faster digestion of the stomach, resulting in too much stomach acid, which will cause damage to the mucosa and lead to stomach pain in the middle of the night. 5, Helicobacter pylori. After the appearance of H. pylori will also cause stomach discomfort, and even diarrhea and other conditions.