Newly crowned asymptomatic infected persons and mildly ill patients are generally not treated specifically, but are observed mainly through centralized isolation. Regular and severe cases require a combination of antiviral and symptomatic treatment. In the case of asymptomatic and mildly ill patients infected with C. neoformans, according to the 9th edition of the C. neoformans Pneumonia Guidelines, no special treatment is given at present, and centralized isolation and observation is the mainstay. Adjunctive treatment, such as Lianhua Qingdian capsule, is only given to infected patients with fatigue and gastrointestinal discomfort. However, if the infected person is ordinary type or there is a risk of turning into severe disease and has already turned into severe disease, ritonavir tablets or monoclonal antibodies are used for antiviral treatment, and dexamethasone immunotherapy and low molecular heparin anticoagulation are used in conjunction with the specific conditions of infected persons. Infected patients who are under medical observation with fatigue and fever can also be combined with Lianhua Qingdian capsule for adjuvant treatment. Specific therapeutic measures and drug selection should be based on the doctor’s instructions, not to use prescription drugs. Tips] This article refers to “new coronary pneumonia, new coronary virus pneumonia”, etc., has been December 26, 2022, the National Health Commission issued a notice to change the name to “new coronary virus infection”.