Taking probiotics for reflux esophagitis does not usually have a significant effect. Reflux esophagitis is mostly caused by damage to the esophageal mucosa and is mainly characterized by heartburn and reflux of gastrointestinal contents. The treatment is mostly acid-suppressing drugs and drugs that promote gastric motility. Probiotics are mostly used to treat the symptoms of gastrointestinal flora disorders, so they are less effective for reflux esophagitis. Since the pathogenesis is not clearly related to intestinal flora disorders, oral probiotics do not help much in the treatment of mucosal damage in reflux esophagitis, so oral probiotics can not alleviate the reflux symptoms of patients with reflux esophagitis. To summarize, taking probiotics has no therapeutic effect on reflux esophagitis, and it is recommended that patients go to the hospital and choose the appropriate treatment under the guidance of professional doctors.