Whether the subpleural nodules in the lower lobes of both lungs are serious needs to be combined with the nodule size, nature, clinical symptoms and other comprehensive judgment, malignant nodules are more serious, benign nodules are generally not serious. 1. The size of the nodule, generally smaller than 6-8mm nodule, the possibility of benign, if the nodule border is clear and single, regular review to observe whether the nodule has changed. If the nodule is accompanied by cough, sputum, chest pain and other symptoms, it is necessary to diagnose and treat the cause and symptoms. 2. The nature of the nodule, if it is a ground-glass nodule, lobed nodule, or there is a burr sign around the nodule, or if there is vascular reconstruction, it needs further examination and treatment. If small subpleural nodules are found in the lower lobes of both lungs, it is recommended that the patient should seek medical treatment in time so as to avoid delaying the disease.