Taking doxycycline for two months may produce drug-resistant reaction, in addition, long-term incorrect use or abuse of antibiotics, may also produce drug resistance, which is mainly related to the drug resistance produced by the germs. Doxycycline is also known as doxycycline, in order to avoid taking doxycycline can produce drug resistance, should be strictly in accordance with the requirements of the doctor to take, can not be unauthorized use of drugs. Also try to avoid unnecessary use and also avoid taking some unscientific way of taking it. Some people taking the drug may affect the digestive system, inducing nausea, vomiting, abdominal pain and other adverse reactions, mild cases can be first observed for a period of time, while severe cases need to be discontinued in time. In addition, it should be contraindicated if you are allergic to the components of the drug or during pregnancy as well as breastfeeding, while children need to be careful with its use. If you need to take antibiotics such as doxycycline hyclate, you should standardize the treatment under the guidance of a professional physician, and strictly follow the doctor’s instructions, to avoid unauthorized use of drugs, causing adverse reactions.