Low-grade intraepithelial neoplasia of the gastric sinus usually cannot be cured by itself and requires treatment. Low-grade intraepithelial neoplasia of gastric sinus is a kind of benign lesion, but this kind of benign lesion has the possibility of cancer, in order to avoid the occurrence of cancer, therefore, it needs to be treated clinically, and usually it can be cured by giving complete surgical resection to the foci of intraepithelial neoplasia of gastric sinus. Low-grade intraepithelial neoplasia of gastric sinus can not be cured by surgery, and if this benign lesion is not treated in time, it will progress to form high-grade intraepithelial neoplasia, and ultimately become cancerous and form gastric cancer. Therefore, once low-grade intraepithelial neoplasia of gastric sinus is detected, it should be treated in hospitals at the earliest possible time.