Omeprazole sodium for injection belongs to proton pump inhibitor, which has the effect of inhibiting gastric acid secretion and protecting gastric mucosa, and is commonly used in the treatment of reflux esophagitis, gastritis, gastric ulcer, duodenal bulb ulcer and other diseases. Long-term intravenous application of omeprazole sodium can cause different side effects, mainly manifested as: 1, hematologic disorders, such as granulocyte deficiency, pancytopenia.2, digestive system reactions, such as nausea, diarrhea, abdominal pain, long-term application can cause atrophic gastritis, individual patients with elevated aminotransferases, hepatic failure, jaundiced hepatitis.3, neurological symptoms, such as dizziness, headache, agitation, depression, hallucinations, abnormal sense of taste.4, musculoskeletal lesions, such as muscle weakness, muscle pain, easily lead to osteoporosis and increase the risk of fracture.5, electrolyte disorders, such as hypomagnesemia, hypocalcemia, hypokalemia.