Toothache at night is worse than during the day may be related to physiologic factors such as psychological and body position, or to pathologic factors such as pulpitis. 1.Physiological factors: (1) Psychological: Because patients need to work, study, live, socialize, etc. during the day, attention is all focused on work and study, the sensitivity to dental pain is weakened; and at night the surrounding environment is quieter and not as busy as during the day, this time is in a relaxed state, so it is more sensitive to dental pain. (2) Body position: because the daytime is often in a sitting position or upright position, the head is in a high position, the blood supply to the head is small, the swelling is not particularly obvious, the pain will not be too obvious; and at night is often in a lying position, the head and the whole body is at the same level, the head and face to withstand more blood, the swelling is obvious, the same pain is also obvious. 2. Pathologic factors: (1) Pulpitis: mainly caused by bacterial infection, physical and chemical stimulation, immune response, etc. It often shows tooth pain, mostly spontaneous pain, pain aggravated at night, and so on. Therefore, it is recommended that people with toothache should choose to consult a doctor in time and follow the doctor’s instructions to standardize the treatment in order to alleviate the symptoms.