Colla Corii Asini is a solid gum made from the dried or fresh skin of donkey, family Equidae, by decocting and concentrating. It is sweet in flavor, flat in nature, and belongs to lung, liver and kidney meridians, with the effect of tonifying blood and nourishing yin, moistening dryness and stopping bleeding. Colla Corii Asini is used in the treatment of blood deficiency, dizziness and palpitation (rapid heartbeat, often accompanied by panic), muscle impotence, insomnia, dry lung cough, coughing, hemoptysis, vomiting blood and urinating blood, blood in stool and leakage of menstruation (menstruation in excessive amount or more than a few drops), and pregnancy leakage of fetus (a small amount of bleeding from the vagina in the early stage of pregnancy). The adverse effects and contraindications of the drug are not clear. If menstruating women experience symptoms such as anemia and irregular menstruation, they can take Agaricus with evidence. If there is a need to use the drug, it is recommended to use it under the guidance of a professional physician to identify the evidence, and not blindly self-medication.