There are many reasons for the phenomenon of sore and tired knees, such as lesions of the quadriceps muscle group in the knee joint area of the patient, due to long-term chronic exertion, strain, trauma, cold and other factors, resulting in old damage to the quadriceps muscle group, which will lead to this phenomenon of soreness and tiredness. The patient is instructed to take proper rest, and at the same time, in the knee joint area, given traditional Chinese medicine fumigation, heat treatment, physical therapy instrument, microwave therapy and other therapeutic means, this phenomenon of soreness and tiredness will gradually be relieved. If the patient’s knee joint is subjected to external force, resulting in biomechanical changes in the knee joint and chondromalacia patella, this phenomenon of soreness and fatigue will also occur. After taking symptomatic treatment, such as instructing the patient to take anti-osteoporosis drugs or blood-activating drugs, it can also relieve this kind of soreness and tiredness.