Taking Bisoprolol heart rate down to 50 beats per minute is generally not dangerous, but this is one of the adverse effects of the drug, so the heart rate drop should be followed by the doctor to stop or reduce the amount of medication. Bisoprolol is mainly used to treat coronary heart disease, arrhythmia and other diseases. Under normal circumstances, the human heart rate should be 60 to 100 beats / min, heart rate fell to 50 beats / min that the drug has induced bradycardia side effects, but this symptom is relatively common in the clinic, the relative safety, the degree of danger is not high, usually in accordance with the doctor’s instructions to adjust the dose of the drug can be. It is not recommended if the patient is allergic to the ingredients or suffers from cardiogenic shock, hypotension, or sick sinus node syndrome. Patients are advised to regularly monitor cardiac, hepatic and renal functions while taking the drug. If the drug needs to be discontinued, the dose of the drug should be reduced as prescribed by the doctor when discontinuing the drug to prevent angina pectoris due to sudden withdrawal of the drug. Bisoprolol heart rate dropped to 50 beats per minute, although the risk is not high, but after the occurrence of this symptom it is still recommended to promptly go to the hospital, ask the doctor whether to adjust the dose of the drug.