Acetaminophen suppositories two hours does not go down the fever can be physical cooling (such as warm water, alcohol wipes, etc.), and recommended timely medical attention, clear cause of the disease, follow the doctor’s instructions for targeted treatment. 1. physical cooling: with acetaminophen suppositories two hours does not go down fever, you can carry out physical cooling, such as warm water, alcohol wipe, etc., at the same time drink more water. 2. Define the cause of the disease: use acetaminophen suppository two hours does not go down the fever is recommended to consult a doctor in time to define the cause of the disease, such as bacterial infections, etc., under the guidance of the doctor to carry out anti-infective treatment (such as oral antibiotics such as cefuroxime tablets), but also under the guidance of the doctor orally antipyretic drugs (such as acetaminophen granules, etc.) Adverse reactions to acetaminophen suppositories include rash, abnormal liver and kidney function, etc. It is contraindicated in patients with severe liver and kidney insufficiency. Acetaminophen suppositories two hours does not reduce the fever is recommended to consult a doctor in a timely manner, under the guidance of a doctor to correct treatment, to avoid delays in the condition.