Diabetic patients are prone to complications such as fungal infections, eczema and other skin lesions due to their low immune system. In addition, high blood sugar levels and dry skin can cause itchy skin. First, control the blood sugar to reach the normal standard. Second, patients should visit a dermatologist to clarify the cause of itching with targeted medication. Eczema is a relatively common skin lesion and can be treated with oral calcium, vitamin C, epalmatine, and topical itching cream with glyburide lotion, and if it is a fungal infection, anti-fungal drugs should be applied symptomatically. Diabetic patients should not wear chemical fiber underwear, but cotton underwear, do not bathe too often and not too long, and the water temperature should be moderate. After bathing, you can apply moisturizing cream to keep the skin moist, avoid smoking and alcohol, and avoid spicy and stimulating food.