Malignant tumors seriously threaten human health, destroy the structure and function of organs and tissues and cause various complications, and cause organ failure of various systems until death when they metastasize widely. It can be said that the treatment of malignant tumors has been a long-standing and unsuccessful problem faced by medical doctors. Among the traditional treatments, surgical resection, chemotherapy and external radiation therapy are the most effective means. However, the limitations of these treatments are: 1. Surgical resection: complete removal of the tumor is the most ideal treatment, but if the resection is not complete or cannot be completely removed (infiltration around large blood vessels and branches or important organs cannot be removed), recurrence will occur. Patients of advanced age, poor physical condition, and those who cannot tolerate anesthesia and surgery also cannot withstand the impact of surgical removal of tumor on their body. 2.Chemotherapy: Chemotherapy is a kind of systemic treatment, which often has poor control effect on local recurrence or tumors that are not completely removed. Moreover, chemotherapy often requires several courses of treatment (weeks to months), which is difficult for tumors with high malignancy and rapid growth and proliferation to be effective. 3.External radiation therapy: External radiation therapy is more effective in local control, but because radiation does not turn around, to completely surround irregular tumors, it needs to cause certain damage to normal tissues and organs, which makes tumors occurring in the vicinity of large blood vessels, spinal cord, urethra, rectum and other structures that tolerate low doses of radiation cannot be effectively treated (increasing the amount of radiation exposure will cause serious complications). complications). Moreover, most external radiotherapy, similar to chemotherapy, requires several cycles to complete, prolonging the treatment time and possibly delaying the optimal treatment of the tumor. Particle implantation technology has been used abroad for more than 100 years and has been written into national treatment guidelines as the first choice and effective treatment modality for many tumors. China is a late adopter of this technology, having just gone through its first decade. Even so, particle implantation has brought great surprises to patients and medical practitioners! In layman’s terms, particle implantation is the process of putting small radioactive particles with therapeutic effects into a metal shell only the size of a grain of rice, and implanting these particles inside the tumor like seeds, so that the therapeutic effect spreads from the inside out. Why do you say that this treatment mode has incomparable superiority to other treatment modes? 1. High dose of local treatment: It is several times higher than the normal external radiotherapy dose and has good local treatment effect. Previously, it was thought that many tumors were not sensitive to radioactivity, so radiotherapy was not considered as the first choice of treatment. Research proves that the reason of insensitivity is that the effective irradiation dose is not reached, but traditional external radiotherapy cannot reach a very high dose most of the time, otherwise, skin radiation damage, normal tissue necrosis, white blood cell drop and other complications will occur. Particle implantation technology is called internal radiotherapy technology, which can kill the tumor from the most central location, which effectively solves the limitation of external radiotherapy that radiation must be delivered to the tumor from outside the body through the skin, subcutaneous, normal tissues and important organ structures. 2.Low damage to normal tissues: Don’t look at the high local dose of particles, but within a very short distance (<2cm), its radiation will rapidly decay, so the surrounding normal structures are protected to the greatest extent, which also enables the eradication of many tumors located in the large blood vessels, spinal cord, urethra and rectum, and other areas where traditional treatment is ineffective, as mentioned earlier. 3.Long therapeutic effect time: The half-life of particles (that is, the time used for half of the therapeutic dose decay) is very long, for example, the commonly used 125-I particles have a half-life of up to 2 months, and these particles will have a continuous killing effect on the tumor for at least half a year, while traditional external radiotherapy and chemotherapy do not have such a long therapeutic effect time. 4.Easy to protect: Some patients are afraid that the radioactive particles implanted into the body will cause radiation to the surrounding people, in fact, there is no need to worry, as already mentioned, the radioactivity is extremely weak, and most of the dose can be attenuated within a very short distance, and the distance beyond one step for normal adults can be attenuated to almost 0. In the process of particle implantation surgery, medical workers only need to wear a layer of paper, as thin as a lead suit. In the process of particle implantation, medical workers only need to wear a layer of paper-like lead suit for effective protection, and many assistants who are one meter away from the patient do not need protection at all, which shows its safety. 5.Shorten the treatment cycle: the time of tumor patients is equal to their lives, and the particle implantation surgery can be completed at one time, which greatly shortens the treatment time and wins the opportunity for the follow-up treatment and recovery of patients as much as possible. It is especially suitable for tumor patients with high malignant degree and fast growth and proliferation. 6.Plannability of surgery: Before the particle implantation surgery, the patient's imaging film (CT or MRI) data should be input into the computer, and the spatial shape of the tumor should be simulated with the help of the software, and how to arrange the particles in the tumor should be the most effective and reasonable. During the surgery, the particles are implanted according to the computer's analysis, so that the implantation process is controllable and reasonable. 7. Patient tolerance (acceptance): The surgery does not require general anesthesia, and most of them can be completed under local anesthesia; the surgery takes two to three hours in long cases, and less than one hour in short cases; these two surgical advantages are especially suitable for the elderly, poor physical condition, and tumor patients who cannot tolerate anesthesia and surgery. Many patients have completed the particle implantation surgery with almost no discomfort, which is a stark contrast to those who have experienced the pain of surgical tumor removal before. 8.Multiple metastases: Many tumor patients are already in the advanced stage when they are diagnosed, and at this time, multiple metastases of the whole body occur. Some patients or family members wrongly think that treatment is unnecessary and take the negative approach of giving up treatment. Some patients think that so many metastases cannot be removed by surgery, so they can only put all their hopes on systemic chemotherapy and other means. Our experience is that particle implantation technology can treat multiple metastases at one time and achieve early control of multiple metastases, and in some cases, a longer survival time can be achieved while ensuring the quality of life. If combined with some other treatments, the effect is more stable. 9. Repeatability of particle implantation surgery: Some cases require secondary implantation, which shows the advantage of repeatability of particle implantation surgery. In cases of recurrence after traditional surgical resection, the rate of re-operation is very low, because the previous operation has caused damage to the anatomical structure of the tumor site, and the field of view of re-operation is disordered, and some structures cannot be finely identified, which causes great difficulties to the operation. In contrast, particle implantation surgery is a minimally invasive surgery, which determines the feature that it can be operated repeatedly but with extremely low destructive effect on human structure. 10.CT-guided particle implantation: CT is the examination method with the highest resolution, which plays a decisive role in the clear display of many tumors. We have been trying to apply CT-guided particle implantation in China for 10 years, and it is the advantage of CT-guided precise and discernible imaging that can effectively guarantee the implementation of particle implantation, which is a strong combination. The advantages of the above 10 types of particle implantation make this technology overcome many limitations of traditional treatment, some scholars named this treatment as "epoch-making" technology, which shows how high it has reached and how much room it has for development. Many foreign scholars have expressed their heartfelt admiration and admiration for the achievements of Chinese medical doctors in applying particle implantation technology to different tumor treatments. At present, only a few hundred regular hospitals in China have carried out particle implantation treatment for malignant tumors, mainly due to the high difficulty of particle implantation surgery, which requires formal training and long-term experience and basic research. Anyway, we need to inform patients about this irreplaceable treatment technology so that they can see some light and hope in the darkness of helplessness!