CT interventional techniques are guided and monitored by computer-aided X-ray tomography, and the lesion is punctured percutaneously with the help of various minimally invasive instruments for examination, biopsy, and treatment; the technique, operation, and accuracy of CT-guided freehand puncture are greatly influenced by experience. Laser guidance and puncture guide assisted CT guidance are easy to operate, accurate to hit, less layers to scan, and less complications; CT guidance stent can keep the puncture needle “aiming” at the lesion, and the puncture hits the target point. This method is easy to operate, has fewer scanning layers, high hit rate and fewer complications. The cannula technique establishes a pathway for biopsy needles to achieve multi-point puncture and multiple sampling, which can obtain a satisfactory and sufficient amount of specimens, and through the cannula needle injection of hemostatic drugs, anti-cancer drugs and medical gum, it can stop hemorrhage and prevent needle tract implantation, which effectively reduces the risk of puncture. Micrometer injection needle punctures inside the tumor through cannula needle, which has less damage and less drug reflux, and improves treatment efficiency. Reduce adverse reactions, CT-guided interventional treatment involves multiple systems, the accuracy rate of CT-guided puncture is 86%-96%, puncture biopsy will not cause tumor dissemination and implantation, and it has become one of the important means to obtain first-level diagnosis clinically, and percutaneous intra-tumor injection will act the drug directly on tumor tissue to achieve treatment purpose. The transdermal ethanol injection and transdermal acetic acid injection have become one of the recognized methods for local treatment of liver cancer, and transdermal hydrochloric acid injection can replace anhydrous ethanol for chemical ablation treatment by using hydrochloric acid, the main component of gastric juice, which has the characteristics of killing cancer cells and coagulating cancer tissues, and the activity of inactivating cancer tissues is 15 times that of anhydrous ethanol. . Percutaneous puncture treatment of liver and kidney cysts can replace the traditional surgical treatment. With the development of CT and MRI interventional puncture technology, imaging tomography minimally invasive diagnosis and treatment expertise will bring progress to medicine.