If you have kidney disease, itching all over the body, if it is early kidney disease, it may be caused by the combination of skin disease; if it is advanced kidney disease, it may be a complication of kidney disease. 1. Early kidney disease: in the early stage of kidney disease, as long as the toxins in the body are gathered in small amount or not gathered, so it will not cause obvious itching symptoms, at this time, itchy skin, generally consider that it is induced by skin diseases. 2. Advanced nephropathy: In the advanced stage, a large number of toxins in the body of patients with nephropathy gather and can not be discharged from the body, which will lead to adverse stimulation of the skin and subcutaneous nerves, or a combination of hyperphosphatemia, secondary hyperparathyroidism, etc., which can cause itchy skin symptoms. It is suggested that patients with kidney disease need to go to regular hospitals to receive relevant examinations, and according to the examination results, receive treatment under the guidance of specialists.