Gout may cause knee pain. Gout is a disease caused by abnormal purine metabolism in the body. Increased production or impaired excretion of uric acid causes elevated blood uric acid, and excess urate crystals are deposited on joints, cartilage, bursae, and other tissues, thus causing recurrent arthritic attacks. In addition to the knee joint, which is a frequent site of gouty arthritis, it can also occur in the first metatarsophalangeal joint, ankle joint, heel, dorsum of the foot and other locations. When gout occurs knee joint involvement, pay attention to rest, reduce the weight of the knee joint, avoid high-purine diet, drink more water, if necessary, timely to the regular hospital, under the guidance of the doctor standardized treatment.