A foreign body sensation in the throat with difficulty in swallowing depends on the following conditions: First, the most common is chronic pharyngitis, which can cause a foreign body sensation in the throat because it affects the pharyngeal plexus or sensory nerves in the throat. However, often it is not obvious or there is a slight difficulty in swallowing, which is completely negligible. Secondly, diseases in the esophagus, such as esophageal tumor, esophageal cancer or esophageal diverticulum, etc. Gastroesophageal reflux resulting in pharyngeal reflux can all present with foreign body sensation and difficulty in swallowing. These conditions should first be thoroughly examined, with electronic laryngoscopy, barium esophageal radiography, or even gastroscopy, etc. There are also other factors, such as thyroid disorders, which can cause foreign body sensation in the throat, and the syndrome of hypertelorism, which can also cause foreign body sensation in the throat and even difficulty in swallowing. Therefore, it is important to first conduct an examination and deal with each case accordingly.