Ear, nose and throat physicians all have experience with children with earaches during the night. We would like to remind parents that, in general, acute otitis media is prone to occur after a cold, sinusitis, acute bronchitis, etc. Because of the low pain threshold at night, acute otitis media is more likely to develop at night. Older children may complain of ear pain, abdominal pain, vomiting, etc. Younger children present with crying, head banging, vomiting, and poor spirits. In the acute stage of earache, there is usually no pus or running water. Once the pus flows, the earache will be relieved, but it also indicates that the condition is somewhat serious. Parents should not panic. If there is a history of prodromal disease, the diagnosis of acute otitis media is basically due to otitis media. Oral ibuprofen (antipyretic) is recommended to relieve the pain, and the dosage can be the same or slightly more than the antipyretic. Phenol glycerin or oxyfluoxacin ear drops without necessarily going to the hospital most of the night. Of course, the next day, even if the child is relieved it is still necessary to go to the hospital.