Middle to advanced squamous lung cancer can usually be treated with the radio wave knife. Radio-wave knife is equivalent to a kind of radioactive treatment, which destroys the growth of tumor by irradiating the tumor lesion area with radiation. Generally speaking, radio wave knife treatment is suitable for patients who are physically weak or in middle or late stage and cannot tolerate surgical operation. Through radio wave knife treatment, lung cancer symptoms can be effectively relieved, and it also has the advantages of being non-invasive, non-anesthesia and short recovery time. The local control rate of radio wave knife treatment can reach more than 80% for patients with locally advanced squamous lung cancer, special tumor growth sites that cannot be radically resected, and advanced cancer patients. It is recommended that patients consult their attending physicians to consider the treatment plan based on their actual conditions and actively cooperate with the treatment as prescribed by doctors.