The most frequent menstruation in women in their fifties is due to the perimenopause, which is a sign that a woman is going through menopause, and to a lesser extent to pathological reasons. When a woman reaches the age of 50, her body’s hormone levels and metabolic levels change significantly, causing significant changes in the rate of endometrial proliferation, which can lead to early or late menstruation. When menstrual bleeding has seriously affected normal life, it is necessary to check the endometrial status by ultrasound, and at the same time, the sex hormone six test can be performed during menstruation to understand the current state of hormone levels, which can be regulated by hormonal drugs such as estradiol. However, there are also certain pathological causes, such as endometrial cancer or cervical cancer, which may cause irregular bleeding or abnormal fluid discharge. Therefore, when there is a significant change in menstrual cycle, it is necessary to go to the hospital for examination first, and if pathological changes are excluded, take measures to stop bleeding and regulate menstruation under the guidance of a doctor.