There are many reasons for cold hands and cold feet, such as heart and kidney disharmony (heart fire, kidney yin deficiency, dysfunction of the physiological functions of the heart and kidneys), yang-qi stagnation, etc., which can lead to the formation of the symptoms of upper heat and lower cold (heat in the upper part and cold in the lower part). Depending on the different identification of the symptoms, traditional Chinese medicines such as Jiaotai Pills, Huanglian Tang, and Sihui San can be chosen to treat the disease. 1. Jiaotai Pill: mainly consists of two medicines, Huanglian and Cinnamon, which have the effects of communicating with the heart and kidney (the heart fire descends and the kidney water rises, which control each other), clearing the heart and tranquilizing the mind (stabilizing the mind by getting rid of the inner heatiness (irritability and sullenness)), and is suitable for those who are suffering from heat in the palm of the hand and coldness in the lower limbs caused by the heart fire being over-excessive and the heart and kidney not communicating with each other, and at the same time, accompanied by dazed and anxiousness (heartbeat being violent, frightening and restlessness), and insomnia. 2. Huanglian Tang: mainly composed of Huanglian, dry ginger, ginseng, cinnamon stick and other medicines, it has the effect of regulating cold and heat, harmonizing the stomach and lowering rebelliousness (regulating the stomach qi and making the upward rebellious qi to descend), and it is suitable for those who have irritable heat in the chest, heat in the palm of the hand, nausea and vomiting, with yellowish reddish coating on the tongue, abdominal pain, intestinal tinnitus, diarrhea, and icy coldness in the lower limbs. 3. Si-Wei San: It is mainly composed of four medicines, namely, Chai Hu, Bai Shao, Citrus aurantium, and Glycyrrhiza glabra, which have the effect of dispersing the liver and regulating the spleen. It is suitable for those who suffer from heat above and cold below, and lack of warmth in the hands or feet due to yang yu syncopation (poor circulation of yang qi leading to coldness of the limbs), and at the same time have pains in the coarseness of the ribs and the hypochondrium (abdomen), with a stringy pulse. As there are more causes of cold hands and feet, if the above symptoms occur, it is recommended to go to the hospital in time, and choose the appropriate medication after diagnosis and identification by a traditional Chinese medicine practitioner, avoiding self-medication, so as to avoid medication that is not appropriate to the condition, aggravating or delaying the condition.