Breast hypoechoic nodule, diagnosed as BI-RADS category 4B (bi-rads category 4B is improperly written), suggests the appearance of malignant signs of the corresponding lesion, which may belong to malignant tumors. The discovery of breast hypoechoic nodules, need to be combined with the morphology of the nodule itself, margins, blood supply status and other comprehensive judgment, BI-RADS 4B class nodule is estimated to have 10% ~ 50% malignant possibility, the clinical will be corresponding to the corresponding nodule to make the diagnosis of BI-RADS 4B class. A puncture biopsy of the corresponding nodule can be performed to further determine the nature of the disease. If BI-RADS 4B is detected in a hypoechoic breast nodule, the patient should be admitted to the hospital in a timely manner for standardized diagnosis and treatment under the guidance of the clinician, so as to avoid any delay in the condition of the patient.