Can a baby with a runny nose get better without medication? For most babies with runny nose, it is known to be a viral infection, and there is actually no effective medicine for viral infection, except for influenza, you can take oseltamivir. However, the systemic symptoms of influenza will be more obvious, such as high fever that does not go away, mental fatigue and so on. If the baby has a clear runny nose and no fever, there is really no need to give special medication, but mainly symptomatic treatment. You can give your baby nasal spray treatment with physiological sea saline, or hot compress with water vapor in the greenhouse, or nebulized inhalation with saline, which can reduce the symptoms of nasal congestion and runny nose. In addition, it is also very crucial to keep the air circulation in the home environment.