Going up stairs with creaking knees may be a physiological phenomenon, but also may be caused by osteoarthritis of the knee joint, chondromalacia patella, and meniscus injuries and other reasons. 1. Physiological factors: when going up the stairs, the cartilage between the patella and the femur will friction and produce a sound, which is a normal physiological phenomenon, the patient will not appear pain and other manifestations. 2. Osteoarthritis of the knee: the cause of osteoarthritis of the knee is not clear, and it is considered to be related to overweight, ageing, congenital joint deformity and other reasons. Patients will have joint pain, limited joint movement, bone rubbing sound and other manifestations, so patients will have creaking knees when going up the stairs. 3. Chondromalacia patella: the cause of chondromalacia patella is not clear, and it is considered to be related to long-term wear and tear of joints, joint malnutrition, joint inflammation and other factors. Patients will have joint pain, bone rubbing sound, knee dysfunction and other symptoms, so that patients will have the symptom of creaking knees when going up the stairs. 4. other: patients on the stairs creaky knees may also be meniscus injury, patellofemoral joint dysplasia, dislocation of the patella and other causes. After eliminating the physiological factors of the creaking knees on the stairs, you need to consult a doctor, who will choose the appropriate measures for the cause of the treatment.