Chickenpox is a disease caused by the varicella-zoster virus infection. Chickenpox on the hands can be treated by oral medication as well as by applying medication. 1. Oral medication: Since chickenpox is caused by viral infection, patients need to take oral antiviral medication under doctor’s instruction, such as acyclovir tablets, ganciclovir dispersible tablets, etc., which can play the role of antiviral. Patients with severe itching can take antihistamines, such as chlorpheniramine maleate tablets and loratadine tablets. 2. Apply drugs: patients can also be coated with antiviral drugs such as Penciclovir cream, phosphonate cream under the guidance of the doctor, and can also be coated with compound dexamethasone cream, Denade cream and other medications, which can play a role in relieving itching. Chickenpox patients must promptly seek medical treatment, pay attention to isolation, while keeping the skin clean can not scratch the skin, so as not to aggravate the patient’s condition.