Stool with blood and mucus may exist in the lower gastrointestinal tract bleeding disorders, mainly including gastrointestinal tract tumors and polyps, inflammatory lesions and anal lesions. 1. Digestive tract tumors and polyps: malignant tumors include cancer, malignant lymphoma, smooth muscle sarcoma, neurofibrosarcoma and so on; benign tumors include lipoma, hemangioma, cystic lymphangioma, mucinous tumor and so on. Polyps are mostly found in the large intestine, with adenomatous polyps as the main ones. 2. Inflammatory lesions: parasitic infections such as amoeba, schistosomiasis, etc.; infectious enteritis such as intestinal tuberculosis, bacillary dysentery, etc.; in addition to ulcerative colitis, Crohn’s disease and so on. 3. Anal lesions: such as hemorrhoids, anal fissure and so on. In addition to the above reasons, the causes of blood and mucus in the stool also include colonic vasodilatation, hemangioma and so on. It is recommended to go to the hospital in time for examination, identify the causes under the guidance of the doctor, and carry out targeted treatment in time.