Blood on the soles of shoes is not usually contagious. If the blood is fresh and contains blood-borne viruses, and happens to come into contact with broken skin or mucous membranes of the human body, it may be contagious, but the probability is extremely low. Common clinical diseases that can be transmitted by blood include AIDS, hepatitis B, hepatitis C, etc. When the virus in the blood leaves the body, it usually cannot survive for a long time, and if it is not fresh blood, the virus is usually already dead. In addition, blood-to-blood contact is required for blood-borne diseases, which means that blood stains on the soles of shoes may become infectious when they come into contact with broken skin and mucous membranes of the human body. Secondly, if the blood on the soles is normal human blood, and there is no infectious virus in the blood, then it is even less infectious. In conclusion, blood on the soles of shoes is usually not contagious, in order to be cautious, you should wear gloves and then wash the shoes contaminated with blood stains, pay attention to clean and disinfect.