Immunoglobulin is an indicator about the growth of the body and one should try to balance the immunoglobulin values as much as possible. Therefore, for low M, it is important to carry out intensive treatment, you can inject gammaglobulin, strengthen exercise, and enhance resistance. In addition to improving the resistance, we should pay attention to let the child exercise more, to ensure sufficient sleep, and to wash hands regularly. Then is to add colostrum to enhance the child’s resistance. For patients with low M, early treatment and early intervention are necessary. In addition, we should identify whether there is multiple myeloma, which requires further bone marrow aspiration to confirm the diagnosis.