The treatment of fracture wound infection and ulceration includes anti-infection treatment, nutritional support and debridement treatment. 1. Anti-infection treatment: if the wound is infected with ulceration, drug sensitivity test can be carried out first, and sensitive antibiotic treatment can be selected to actively control the infection and avoid further aggravation of ulceration. 2. Nutritional support: when the wound infection occurs, it is necessary to supplement the nutrition in time to avoid excessive consumption of the patient by the infection and the emergence of anemia and hypoproteinemia. 3. Cleansing treatment: when the wound is infected and ulcerated, the wound should be disinfected and cleansed in time to remove the decayed and necrotic tissues to avoid further aggravation of necrosis, and the wound should be changed regularly, and if necessary, it can be sutured, implanted with skin or flap transplantation. When the fracture wound is infected, it is necessary to consult the doctor in time and carry out standardized treatment under the doctor’s guidance to avoid further aggravation of the condition and danger.