The common reasons for hand swelling and pain after waking up include the following: First, blood circulation, including incorrect posture during sleep at night to compress the upper limbs, resulting in poor blood circulation or the presence of vasculitis and other diseases in the upper limbs, which affects blood circulation, resulting in poor local circulation of blood stagnation, the accumulation of metabolites can not be excreted in a timely manner, and swelling and pain will occur in the morning. Second, it can be seen in peripheral nerve diseases, including upper limb neuritis, local inflammation, cervical spondylosis leading to nerve root compression in the upper limb, which can involve nerve problems, resulting in morning distension and pain. Thirdly, other diseases seen in the whole body, such as hypertension, atherosclerosis, renal insufficiency, etc., can also cause a feeling of morning swelling and pain due to abnormal circulation and water and sodium retention. Patients are advised to go to the hospital for detailed examination and to make a clear diagnosis based on medical history, accompanying symptoms, physical examination by a doctor and auxiliary examinations.