Vomiting after intoxication should first keep the airway open to avoid vomit from entering the respiratory tract and serious situations such as misaspiration, choking and even asphyxiation. Appropriate glucose water of about 100ml should be given orally. For those who vomit violently and cannot be treated orally, intravenous rehydration can be used, mainly by giving isotonic glucose, and diluted hypertonic glucose solution to accelerate the metabolism of alcohol. Antiemetic drugs, such as metoclopramide and granisetron, can be given to patients who vomit violently and repeatedly. In addition, for gastric mucosal damage due to violent vomiting and alcohol stimulation, fasting and stomach acid suppressants such as cimetidine, omeprazole, lansoprazole, and pantoprazole should be given to avoid stomach acid irritation of the gastric mucosa. If necessary, wake-promoting drugs such as naloxone should be given to reduce the inhibitory effect of alcohol on the brain.