The first is whether the patient can tolerate the surgery. If the patient also suffers from severe progressive neurodegenerative diseases or metabolic diseases, as well as malnutrition, or if the patient also suffers from severe cardiovascular diseases, respiratory insufficiency, or coagulation disorders, the surgery is not recommended. These diseases include: myocardial infarction, severe arrhythmia, respiratory failure, uremia, hemophilia, thrombocytopenia, etc. Secondly, if the patient has severe mental disorders and intellectual disabilities, they are also not suitable for surgery. It is important to note that anxiety and depression, as well as psychiatric disorders, are often co-morbidities in epilepsy, and intellectual developmental disorders are also common in children with epilepsy. Therefore, pre-surgical assessment of mental and intellectual abilities is necessary.