The side effects of long-term use of Stone Dispelling Granules are not clear. Stone-discharging granules are mainly composed of Psyllium, Xu Changqing, Lianqiancao, Shiwei, Talc, Lonicera, Qu Mai and other traditional Chinese medicines, which have the efficacy of clearing heat and inducing diuresis, and can be clinically used for the treatment of stone-discharging caused by dampness-heat in the lower Jiao (discharging sand and stones during urination, or urination suddenly interrupted, with pain in the urethra, intolerable lumbar and abdominal cramping pains), which are characterized by dysuria or accompanied by hematuria, and pain in the lumbar and abdominal area, etc. The adverse effects and contraindications are not yet clear. The adverse reactions and contraindications of Pai Shi Granule are not clear, and it is forbidden for those who are allergic to its ingredients. Whether patients need long-term use of Pai Shi Granules should follow the doctor’s instructions. Pai Shi Granules should be used under the diagnosis of traditional Chinese medicine, and should not be used blindly by oneself to avoid causing damage.