The 5-year survival period of patients with stage III rectal cancer is 50-70%, and some patients can survive for a long time. Stage III rectal cancer indicates that the patient has developed regional lymph node metastasis, and the patient should actively undergo surgical treatment to remove the primary site of the malignant tumor and the surrounding lymph nodes. After the surgery, if the treatment can be actively carried out, the 5-year survival period of most of the patients will be 50~70%, and a few patients may have a longer survival period, and they can survive for a long period of time. The specific survival time of patients with stage III rectal cancer is affected by many factors, such as the underlying physical quality, whether it is accompanied by other serious diseases, etc., which will affect the survival time of patients, and the survival time of patients with multiple diseases may be appropriately shortened. Patients with stage III rectal cancer should actively go to the hospital for consultation, and under the guidance of physicians, undergo surgery and drug chemotherapy to prolong the survival time of patients.