Pain in the ear can usually be treated with oral aminoglutethimide tablets, clofentezine tablets or ibuprofen extended-release capsules. After the onset of pain in the ear, it is necessary to go to the hospital for an electronic otoscopy to check whether there is otitis externa or otitis media. If the diagnosis of otitis externa or otitis media caused by pain in the ear, need to carry out electrical audiometry to check whether there is fluid in the middle ear, if necessary, can be carried out in the middle ear tympanic cavity puncture, the external auditory canal can be drops of of ofloxacin ear drops, twice a day. If exclude otitis media or otitis externa caused by the pain in the ear, usually the ear pain caused by otoneural neuralgia, can take oral ibuprofen extended-release capsules to relieve pain. Usually, after one week of systematic treatment, the pain in the ear will disappear completely, and sleep should be guaranteed during the treatment period.