Clinical manifestations and pharmacological treatment of inadequate vertebral artery blood supply

The main clinical manifestations of vertebral artery insufficiency are dizziness, headache, sometimes accompanied by irritability, insomnia, tinnitus, retrograde amnesia, memory loss, inattention and so on. The causes of chronic cerebral insufficiency are complex, including arteriosclerosis, arteritis, arterial stenosis, hypertension, hypotension, hyperlipidemia, diabetes, anemia, etc. Obesity and smoking are also contributing factors to the formation of chronic cerebral insufficiency. Treatment of cerebral insufficiency should focus on protecting the remaining neurological functions, improving and restoring the damaged neurological functions, and preventing them from developing into more severe types of cerebral ischemia. Drug therapy: Calcium channel blockers commonly used in the treatment of cerebral ischemic vascular lesions include nimodipine, nicardipine and flunarizine, etc.; histamine pethidine has a more obvious dilating effect on cerebrovascular and cardiovascular, especially on vertebrobasilar system, which can significantly increase blood flow in the heart, brain and peripheral circulation, improve blood circulation and lower systemic blood pressure, and also has a slight diuretic effect. It can increase blood flow and unblock blood vessels, which is effective in ischemic encephalopathy; anticoagulants and anti-platelet aggregation agents (such as sodium bis-alginate, aspirin, etc.) can reduce the formation of obstructive thrombus in peripheral arteries; Chinese patent medicines (such as Ginkgo biloba, Astragalus, Chuanxiongzin, etc.) can improve the clinical symptoms of cerebral arteriosclerosis and reduce blood lipids and blood viscosity.